What Is in a Myers' Cocktail?

The complete ingredient guide to the most evidence-based IV therapy protocol, developed by Dr. John Myers at Johns Hopkins.

The Myers' Cocktail is the gold standard of IV therapy — a carefully balanced formula of magnesium, calcium, B vitamins, and vitamin C in a sterile saline base. Developed by Dr. John Myers in the 1960s and published by Dr. Alan Gaby, it remains the most studied and widely offered IV drip in the world.

Myers' Cocktail Ingredients

IngredientTypical DoseFunction
Magnesium Chloride200–400mgMuscle relaxation, energy production, migraine prevention, supports 300+ enzymatic reactions
Calcium Gluconate100–200mgBone health, nerve function, muscle contraction, cardiac function
B-Complex VitaminsB1, B2, B3, B5, B6Energy metabolism, neurotransmitter synthesis, red blood cell production
Vitamin B12 (Methylcobalamin)1,000–5,000mcgNerve health, DNA synthesis, energy, mood regulation
Vitamin C (Ascorbic Acid)2,000–10,000mgImmune support, collagen synthesis, antioxidant protection
Sterile Saline or Sterile Water250–500mLHydration base, electrolyte balance, vehicle for other nutrients

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Myers' Cocktail — Frequently Asked Questions

The Myers' Cocktail was developed by Dr. John Myers, a physician at Johns Hopkins University, who used IV nutrient therapy from the 1960s until his death in 1984. The protocol was later documented and published by Dr. Alan Gaby, who continued and refined the formula. It remains the most evidence-based IV therapy protocol available.
The Myers' Cocktail has published research supporting its use for: fatigue and chronic fatigue syndrome, fibromyalgia, acute and chronic migraines, upper respiratory infections, asthma attacks, seasonal allergies, cardiovascular disease support, and general micronutrient deficiency replenishment.
For general wellness, monthly Myers' Cocktail infusions are common. For specific conditions (migraines, fibromyalgia, chronic fatigue), providers often recommend weekly sessions for 4–8 weeks, then biweekly or monthly maintenance. Many wellness-focused individuals get biweekly sessions as a proactive health strategy.
A Myers' Cocktail IV drip typically costs $149–$275 per session. Prices vary by location, clinic type, and add-ons. Monthly memberships at IV clinics can reduce per-session costs to $99–$149. Mobile Myers' Cocktail delivery adds $20–50.
The Myers' Cocktail is a specific, evidence-based formulation of magnesium, calcium, B vitamins, and vitamin C developed by Dr. John Myers. Other drips target more specific goals: a hangover drip focuses on hydration and anti-nausea; an immunity drip emphasizes high-dose vitamin C and zinc; NAD+ is specifically for cellular energy and anti-aging.