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Ozone IV Therapy IV Therapy in South Sioux City, Nebraska

Oxygen-rich therapy for cellular regeneration

Medically reviewed by Jonathan Belmore, MD|Updated 2026-06-01
$150 – $350 per session~60 minutesSouth Sioux City, NE
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What is Ozone IV Therapy IV Therapy?

Ozone IV therapy (also called Major Autohemotherapy or MAH) involves drawing blood from the patient, exposing it to medical-grade ozone gas, and reinfusing the ozonated blood. Ozone (O3) reacts with blood components to produce bioactive molecules that stimulate antioxidant defense systems, enhance oxygen delivery to tissues, modulate the immune system, and exert antimicrobial effects. Used in integrative medicine for chronic infections, Lyme disease, autoimmune conditions, chronic fatigue, and as a general wellness and anti-aging protocol.

Key Benefits

  • Enhanced oxygen delivery to tissues
  • Antioxidant enzyme stimulation
  • Immune system modulation
  • Antimicrobial effects
  • Chronic infection support
  • Anti-inflammatory activity
  • Cellular energy enhancement

Best For

  • Chronic Lyme disease support
  • Chronic viral infections
  • Autoimmune condition support
  • Anti-aging and longevity
  • Chronic fatigue and fibromyalgia
  • Mold illness recovery
  • General integrative wellness

Ozone IV Therapy Pricing in South Sioux City

Local pricing estimates based on market data for South Sioux City, Nebraska.

Starting From

$150

Typical High

$350

Session Length

60 min

Prices vary by provider, add-ons, and mobile vs. clinic delivery. Mobile services may add a $25–$50 travel fee.

What's in a Ozone IV Therapy IV Drip?

Medical-grade Ozone Gas (O3)Patient's Own Blood (autohemotherapy)Normal Saline (for IV ozone drips)

Ozone IV Therapy IV Providers in South Sioux City

20 listed

ELC Center

Medical Clinic
No ratings yet
113 E 20th St, South Sioux City, NE 68776, USA
endolifecare.com/?utm_source=sioux-city
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UnityPoint Clinic Infusion Center – Sunnybrook

Medical Clinic
No ratings yet
5885 Sunnybrook Dr, Sioux City, IA 51106, USA
(712) 266-2610
unitypoint.org/locations/unitypoint-clinic-infusion-center--sunnybrook?utm_source=gmb&utm_medium=web&utm_campaign=brandify
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The Sonography Studio - Sioux City

Medical Clinic
5.0(177 reviews)
922 4th St, Sioux City, IA 51101, USA
(712) 487-4530
thesonographystudio.com/
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No Filter Aesthetics

MedSpa
5.0(77 reviews)
611 Pearl St, Sioux City, IA 51101, USA
(712) 490-9704
nofilteraestheticssiouxcity.com/
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Vibrance Medical, PLLC

Medical Clinic
5.0(16 reviews)
101 Tower Rd #103, Dakota Dunes, SD 57049, USA
(605) 534-4043
vibrancemedical.com/
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Encompass Wellness & Aesthetics

Medical Clinic
5.0(15 reviews)
319 Dakota Dunes Blvd Ste. B, North Sioux City, SD 57049, USA
(605) 740-0414
encompass-wellness.com/?utm_source=google&utm_medium=organic&utm_campaign=gbp
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Sharae's Spathecary L.L.C.

Medical Clinic
5.0(26 reviews)
521 W 9th St, South Sioux City, NE 68776, USA
(712) 899-5164
sharaesspathecary.com/
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New You MedSpa

MedSpa
5.0(5 reviews)
317 Dakota Dunes Blvd Suite D, North Sioux City, SD 57049, USA
(605) 418-8409
new-you-medspa.square.site/
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Yoni Restorative LLC

Wellness Center
5.0(3 reviews)
1524 Military Rd, 3500 S Lakeport St, Sioux City, IA 51103, USA
(712) 444-0995
yonirestorative.com/
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Thrive Wellness Center

MedSpa
5.0(161 reviews)
819A Gordon Dr, Sioux City, IA 51101, USA
(712) 224-9355
thrivewellnesscenter.net/
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ALIVE Hydration Spa

MedSpa
5.0(2 reviews)
305 Dakota Dunes Blvd, Dakota Dunes, SD 57049, USA
livebetterwithalive.com/
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Lace & Needle

MedSpa
5.0(119 reviews)
326 W 25th St, Sioux City, IA 51104, USA
(712) 383-8528
laceandneedle.com/
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ivclub - iv&co.

MedSpa
5.0(65 reviews)
345 S Reid St STE. 123, Sioux Falls, SD 57103, USA
(605) 271-0715
ivclub.com/
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LIVE Hydration Spa Sioux Falls

MedSpa
5.0(24 reviews)
5011 S Louise Ave, Sioux Falls, SD 57108, USA
(531) 999-3030
livehydrationspa.com/live-hydration-spa-sioux-falls/
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Vital Flow Infusions

MedSpa
5.0(258 reviews)
119 S Main Ave, Sioux Falls, SD 57104, USA
(605) 223-1503
vitalflowinfusions.com/?utm_source=google&utm_medium=organic&utm_term=gbp-listing
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Prime IV Hydration & Wellness - Sioux Falls

Wellness Center
4.9(56 reviews)
7208 S Lyncrest Pl, Sioux Falls, SD 57108, USA
(605) 231-9263
primeivhydration.com/locations/south-dakota/sioux-falls-57108/
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Prosper Health and Aesthetics

MedSpa
4.9(373 reviews)
5402 Morningside Ave, Sioux City, IA 51106, USA
(712) 639-6304
prosperdirecthealth.com/?y_source=1_MTA2NDg3NDE5Ny03MTUtbG9jYXRpb24ud2Vic2l0ZQ%3D%3D
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Chapter Aesthetic Studio

MedSpa
4.9(113 reviews)
5001 Sergeant Rd, Sioux City, IA 51106, USA
(712) 220-0670
mychapter.com/
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Ave Medical Laser Spa

MedSpa
4.7(138 reviews)
1201 4th St, Sioux City, IA 51101, USA
(712) 224-3500
avemedspa.com/?y_source=1_MjgxMzA0NDMtNzE1LWxvY2F0aW9uLndlYnNpdGU%3D
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RE-SET IV HYDRATION

MedSpa
4.5(2 reviews)
2001 Broadway Ave, Yankton, SD 57078, USA
(605) 689-2273
resetivhydration.com/
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FAQ — Ozone IV Therapy IV Therapy in South Sioux City

Ozone IV Therapy IV therapy in South Sioux City, Nebraska typically costs $150–$350 per session. Mobile visits usually add a $25–$50 travel fee, and add-ons or multi-session packages can change the total.
We're still adding Ozone IV Therapy providers in South Sioux City. Submit a quote request and we'll connect you with available local IV therapy providers as they come online.
A Ozone IV Therapy IV session in South Sioux City typically takes about 60 minutes, plus 10–15 minutes for intake at your first visit.
Ozone IV Therapy is most often used for Chronic Lyme disease support, Chronic viral infections, Autoimmune condition support, Anti-aging and longevity. Ozone IV therapy (also called Major Autohemotherapy or MAH) involves drawing blood from the patient, exposing it to medical-grade ozone gas, and reinfusing the ozonated blood.
Ozone IV Therapy IV therapy is generally safe when administered by a licensed RN or NP at a reputable South Sioux City provider operating under a medical director. It may not be appropriate for people with G6PD deficiency (absolute contraindication), Active bleeding or hemorrhage, Hyperthyroidism (untreated) — always complete a health intake first.
Our current South Sioux City listings for Ozone IV Therapy are in-clinic, but mobile IV service is expanding across Nebraska. Ask local providers about home or hotel delivery, which usually adds a $25–$50 travel fee.

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