Ozone IV Therapy IV Therapy in Middleburg, Florida

Oxygen-rich therapy for cellular regeneration

Medically reviewed by Jonathan Belmore, MD|Updated 2026-06-01

$150 – $350 per session~60 minutesMiddleburg, FL

What is Ozone IV Therapy IV Therapy?

Ozone IV therapy (also called Major Autohemotherapy or MAH) involves drawing blood from the patient, exposing it to medical-grade ozone gas, and reinfusing the ozonated blood. Ozone (O3) reacts with blood components to produce bioactive molecules that stimulate antioxidant defense systems, enhance oxygen delivery to tissues, modulate the immune system, and exert antimicrobial effects. Used in integrative medicine for chronic infections, Lyme disease, autoimmune conditions, chronic fatigue, and as a general wellness and anti-aging protocol.

Key Benefits

Enhanced oxygen delivery to tissues
Antioxidant enzyme stimulation
Immune system modulation
Antimicrobial effects
Chronic infection support
Anti-inflammatory activity
Cellular energy enhancement

Best For

Chronic Lyme disease support
Chronic viral infections
Autoimmune condition support
Anti-aging and longevity
Chronic fatigue and fibromyalgia
Mold illness recovery
General integrative wellness

Ozone IV Therapy Pricing in Middleburg

Local pricing estimates based on market data for Middleburg, Florida.

Starting From

$150

Typical High

$350

Session Length

60 min

Prices vary by provider, add-ons, and mobile vs. clinic delivery. Mobile services may add a $25–$50 travel fee.

What's in a Ozone IV Therapy IV Drip?

Medical-grade Ozone Gas (O3)Patient's Own Blood (autohemotherapy)Normal Saline (for IV ozone drips)

Ozone IV Therapy IV Providers in Middleburg

19 listed

ELMNT Wellness

MedSpa

5.0(21 reviews)

1638 Corsair Ln Suite 305, Middleburg, FL 32068, USA

(904) 413-7006

elmntwellness.com/

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Revive & Thrive Wellness

Wellness Center

5.0(6 reviews)

4465 US-17 suite 127, Fleming Island, FL 32003, USA

(904) 400-9748

optimantra.com/optimus/patient/patientaccess/servicesall?pid=M1dLM3FjbVN2aEtoKy84d3oybHJPQT09&lid=Y0luVFlidGlaY1Z4OWZ3UlV1K29HQT09

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FYZICAL Therapy & Balance Centers Middleburg

Medical Clinic

5.0(9 reviews)

2620 Blanding Blvd Ste. 11, Middleburg, FL 32068, USA

(904) 406-0037

fyzical.com/middleburg-fl

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Natural Body Wellness Clinic

Wellness Center

5.0(37 reviews)

534 Park Ave STE 6, Orange Park, FL 32073, USA

(904) 999-1363

naturalbodywellnessclinic.com/

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Restore Hyper Wellness

MedSpa

5.0(353 reviews)

1615 County Rd 220 #140, Fleming Island, FL 32003, USA

(904) 830-1520

restore.com/locations/fl-fleming-island-fl054?utm_source=gmb&utm_medium=Yext&y_source=1_MTAwMzc1NTcxOS03MTUtbG9jYXRpb24ud2Vic2l0ZQ%3D%3D

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Infuse-You

IV Bar

5.0(46 reviews)

7858 Island Fox Rd, Jacksonville, FL 32222, USA

(904) 752-1855

infuseyou.net/

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IVX Health Infusion Center

Medical Clinic

5.0(104 reviews)

10400 San Jose Blvd APT 13, Jacksonville, FL 32257, USA

(904) 339-7332

ivxhealth.com/locations/florida/jacksonville/mandarin?utm_source=gmb&utm_medium=yext

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Prime IV Hydration & Wellness - Jacksonville FL

MedSpa

5.0(16 reviews)

11111 San Jose Blvd Suite 70, Jacksonville, FL 32223, USA

(904) 664-9260

primeivhydration.com/locations/florida/jacksonville-32223/

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Drip Refresh Mobile IV Therapy - Jacksonville

Mobile Service Mobile Available

5.0(1 reviews)

1514 N Pearl St, Jacksonville, FL 32202, USA

(904) 664-1286

driprefreshmobileiv.com/mobile-iv-therapy-jacksonville-florida

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Livality Integrated Health

Medical Clinic

5.0(28 reviews)

1620 Corsair Ln Suite 201, Middleburg, FL 32068, USA

(904) 787-8850

livalityhealth.com/

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Bella Lei Aesthetics & Optimal Wellness

MedSpa

5.0(542 reviews)

1540 Business Center Dr Suite C, Fleming Island, FL 32003, USA

(904) 579-4323

bellaleiaesthetics.com/

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H2 Health- Middleburg, FL

Medical Clinic

4.9(362 reviews)

2710 Blanding Blvd #305, Middleburg, FL 32068, USA

(904) 282-8640

h2health.com/locations/h2-health/middleburg-fl/

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Rebound Rehabilitation - Middleburg

Medical Clinic

4.9(67 reviews)

1821 Blanding Blvd Suite 2, Middleburg, FL 32068, USA

(904) 561-2544

reboundrehab.com/location/physical-therapy-middleburg-fl/

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Pura Vida Body & Mind Spa

MedSpa

4.9(1,121 reviews)

1590 Island Ln Suite 28, Fleming Island, FL 32003, USA

(904) 293-1692

puravidaflemingisland.com/procedures

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Thrive Infusions

MedSpa

4.9(1,493 reviews)

4888 Town Center Pkwy #104, Jacksonville, FL 32246, USA

(904) 646-8357

thriveinfusions.com/

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North Florida Stem Cells

Medical Clinic

4.8(57 reviews)

421 Kingsley Ave STE 200, Orange Park, FL 32073, USA

(904) 215-5800

northfloridastemcells.com/

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Coastal Health NexStep - Middleburg

IV Bar

4.8(32 reviews)

1811 Blanding Blvd Suite 102, Middleburg, FL 32068, USA

(904) 288-8311

coastalhealth.com/

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4Ever Young Med Spa & Wellness Center - Fleming Island

MedSpa

4.8(173 reviews)

1845 E West Pkwy #17, Fleming Island, FL 32003, USA

(904) 921-2442

4everyoungantiaging.com/fleming-island/?utm_source=google&utm_medium=organic&utm_campaign=gbp-fleming-island

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Hometown Health & Wellness, LLC

Wellness Center

4.6(11 reviews)

4443 Co Rd 218 unit 101, Middleburg, FL 32068, USA

(352) 664-7702

hometown-hw.com/

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FAQ — Ozone IV Therapy IV Therapy in Middleburg

Ozone IV Therapy IV therapy in Middleburg, Florida typically costs $150–$350 per session. Mobile visits usually add a $25–$50 travel fee, and add-ons or multi-session packages can change the total.

We're still adding Ozone IV Therapy providers in Middleburg. Submit a quote request and we'll connect you with available local IV therapy providers as they come online.

A Ozone IV Therapy IV session in Middleburg typically takes about 60 minutes, plus 10–15 minutes for intake at your first visit. Mobile providers usually arrive within 45–90 minutes of booking, so you can relax at home during the infusion.

Ozone IV Therapy is most often used for Chronic Lyme disease support, Chronic viral infections, Autoimmune condition support, Anti-aging and longevity. Ozone IV therapy (also called Major Autohemotherapy or MAH) involves drawing blood from the patient, exposing it to medical-grade ozone gas, and reinfusing the ozonated blood.

Ozone IV Therapy IV therapy is generally safe when administered by a licensed RN or NP at a reputable Middleburg provider operating under a medical director. It may not be appropriate for people with G6PD deficiency (absolute contraindication), Active bleeding or hemorrhage, Hyperthyroidism (untreated) — always complete a health intake first.

Yes — at least one Middleburg provider in our directory offers mobile Ozone IV Therapy that comes to your home, hotel, or office, typically arriving within 45–90 minutes of booking.

Find IV Therapy Providers in Middleburg

Compare local clinics and mobile IV services. Free, no-obligation quotes.